Discussion: The Human Genome
Discussion: The Human Genome
Discussion: The Human Genome
ORDER NOW FOR AN ORIGINAL PAPER ASSIGNMENT: Discussion: The Human Genome
Human Genome Editing
What types of editing should be allowed to the human genome? This discussion is prompted by the U.S. National Academies of Sciences, Engineering, and Medicine report titled Human Genome Editing: Science, Ethics, and Governance in February 2017 (the Summary from that report is provided below). While not having the authority to regulate such activities, the publication lays out considerations to guide government regulators and legislators as they establish the uses and parameters for human germline editing.
The current state of human genome editing (with special regard for the CRISPR/Cas9 technology described in the figure below), along with ethical, legal, and regulatory considerations of gene-editing technology, are in flux. The report prefaces the discussion in this way:
Clinical trials using edited human somatic cells are already underway, and more are anticipated. To help direct the use of genome editing toward broadly promoting human well-being, it is important to examine the scientific, ethical, and social issues it raises, and assess the capacity of governance systems to ensure the technologies’ responsible development and use. Doing so also entails articulating the larger principles that should underlie such systems.
Three background articles accompany this paper. The first describes the first successful manipulation of a human embryo using the CRISPR/Cas9 technology. The second article summarizes a survey of current US attitudes on human genome editing. The third article questions whether human genome editing should occur at all.
NOTE: Prior to beginning this Discussion Board, please view this short YouTube summary of the CRISPR/Cas9 system: https://www.youtube.com/watch?v=2pp17E4E-O8
Answer these DISCUSSION PROMPTS :
What types of editing should be allowed to the human genome?
What other applications of CRISPR technology can you envision?
Do you foresee any unintended consequences of human or other genome editing?
READINGS
CRISPR fixes disease gene in viable human embryos 2017.pdf
Human CRISPR Trials Will Happen in 2018.pdf
Human Genome Editing – Science Ethics and Governance 2017.pdf
Should you edit your childrens genes 2016.pdf
Summary NASEM Report pp 1-14 2017.pdf
Summary of Principles and Recommendations NASEM Report pp 181-194.pdf
DIAGRAM and Readings will be attached seperately!
Assignment Policies
Description
Class-
Please read all of the information about the assignments below:
FORMAT FOR ALL ASSIGNMENTS
The assignments are to be done in Microsoft Word with Times New Roman 12- point font. Each assignment should use the modified APA 6th edition format. The assignment templates are set up in this modified format. The reference page should be in the APA format for every reference. The word requirement for the assignments are specifically stated in the guidelines of the assignment. The word count is from the first word of the introductory paragraph to the last word of the conclusion paragraph. FYI.
REFERENCE REQUIREMENTS
1- There should be a cited reference for each section of a paper as there are conclusion statements in each section (to meet the grading criteria) so the conclusion should be supported by a reference as the assignments are evidence-based research, clinical papers.
2- Word Count- The word count is done from the first word of the introductory paragraph to the last word of the conclusion. The word count must be within the minimum and maximum word limit stated in the assignment instructions. A 10% – point reduction will be made in the total points for the assignment.
Week 1 and 5 assignments should have SIX studies. Week 5 assignment is a compilation of sections from the week 1, 2 & 3 assignments.
Weeks 2 and 3 need to have at least THREE studies in the form of research studies. Please make sure that you look at the instructions for the assignment as well as the grading rubric. I have also provided templates for ALL assignments. It is in your best interest to use these as it will guide you so that you do not make common formatting errors.
APA FORMAT FOR ASSIGNMENT
Please utilize the resources in the STUDENT SUCCESS CENTER if you have difficulty with APA 6th Edition format, grammar, sentence structure, punctuation or tense structure.
SUBMISSION OF ASSIGNMENTS
Always submit the assignment in the drop box for that assignment. I cannot accept any assignment as an attachment to an email sent to my college email. Attaching it to a posting to the Questions to Instructor Forum or the Individual Forum is also not accepted.
I cannot grade any assignment unless it is placed into the drop box by the student per university policy.
Turn-It-In / Lopes Write
This is to be used for the assignments for these three weeks (2, 3 & 5) and it is NOT required for Week 1. All assignments will be placed through Turn It In first and then submitted in the drop box on the course shell. No assignments will be accepted as attachments to emails as this is not the university policy.
Grading Rubric-
The rubric for each assignment is found in the upper right- hand corner of the assignment page under the Forum Tab. Compare the requirements of the rubric with your paper prior to submission into the drop box so you will receive full credit for all graded criteria of the paper.
Late Assignment-
Any assignment that is late will have 10% deducted each day it is late. This is a 5- week class. It is imperative that you ask for help if you are having difficulty with an assignment.
You need to contact me as soon as possible if an assignment will be late prior to the submission deadline.
